This article provides kinetic constants for C-terminal processing of procollagen type I by bone morphogenetic protein Echinacea 1 (BMP-1; the major procollagen C-proteinase), a reaction stimulated by the connective tissue glycoprotein procollagen C-proteinase enhancer 1 (PCPE-1).Reported are Km, Vmax, Kcat and Kcat/Km (catalytic coefficient) WOMENS

The basal hadrosauroid Tethyshadros insularis from the uppermost Cretaceous of NE Italy lived on an island of the European archipelago in the Tethys Ocean.The tail of this dinosaur presents several apomorphic traits respect to the tails of other coeval hadrosauroids of the archipelago and of hadrosauroids in general.The estimated total length of th

BACKGROUND Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease.Autoimmune mechanisms may contribute to its pathogenesis.We diagnosed several cases of systemic autoimmune diseases among Bolivian migrants in Geneva with a high prevalence of Chagas disease.OBJECTIVES We tested the hypothesis of a clinical association between sy

Capacity uncertainty is a common issue in the transportation planning field.However, few studies discuss the intermodal routing problem with service capacity uncertainty.Based on our previous study on the intermodal routing under deterministic capacity consideration, we systematically explore how service capacity uncertainty influences the intermod

Introduction: Tracheostomy is commonly performed for upper airway obstruction, prolonged mechanical ventilation and tracheo-bronchial toileting.Pediatric tracheostomy differs from adult tracheostomy in terms of surgical procedure, post-operative care and recovery.The tracheostomized patients may either be decannulated, discharged with tube-in-situ